Date: 7 March 2023
Talk 1: Breathable skin electronics for human health monitoring
Speaker: Yan Wang
One limitation of commercialized wearables, such as smartwatches and bands, is that they cannot form conformable contact with human skin due to their rigid form factor, thereby limiting their monitoring capabilities. Soft bioelectronics, on the other hand, are touted as an ideal platform for personalized health care owing to unique characteristics, such as thinness, lightweight, good biocompatibility, excellent mechanical robustness, and great skin conformability. Permeable skin-mountable electronics that are capable of long-term applications have emerged as promising tools for early disease prevention, screening, diagnosis, and treatment. Dr. Wang’s research interests mainly focus on the development of wearable electronics for biomedical health monitoring, including stretchable conductors, sensors, and soft energy devices. In today’s talk, she will introduce high-performance skin bioelectronics developed by ultrasoft nanomesh systems, which can realize the accurate measurement of minus skin deformations and finger touch without disturbing natural skin motions and sensations, as well as long-term applications for health monitoring.
Dr. Yan Wang joint Guangdong Technion, Department of Chemical Engineering as an Associate Professor in Nov. 2021. She received her Ph.D. degree majoring in Chemical Engineering from Monash University in 2018 and completed her postdoc training at the Department of Electrical and Electronic Engineering, the University of Tokyo, in 2021. In soft electronics field, Dr. Yan Wang has published over 40 scientific articles in flagship journals like Science, Nature Electronics, Science Advances, PNAS, Chemical Society Reviews, ACS Nano, etc., granted 1 Australia patent, and won several scientific awards, such as 2018 Outstanding Self-financed Students Abroad. Her research works were featured by renowned CNN, Science, major Australian media such as Herald Sun, and Japanese medias such as Nikkan Kogyo Shimbun. At Guangdong Technion, her group mainly focuses on materials development and the practical implementation of soft wearables in real-life situations towards ambulatory health care and the Internet of Things.
Talk 2: Multi-modality Monitoring and Personalized Brain Protection in Neuro Intensive Care Unit
Speaker: Xiuyun Liu
The neuro intensive care unit (NICU) holds the most severe patients, therefore, the nurses in NICU must closely monitor each patient’s progress via various equipment. The brain is hypoxically intolerant, which needs constant and continuous supply of cerebral blood flow. How to ensure sufficient blood flow supply to the brain through multimodality monitoring, including intracranial pressure monitor, cerebral oxygen monitor, cerebral blood flow velocity monitor, etc., is a critical problem in NCIU. In addition, due to the different living environment, personal habits and history of diseases, the optimal level of blood flow varies among different patients. Individualized diagnosis and assessment of brain state plays an important role in brain protection, which will improve patient outcome. This workshop will introduce several basic topics about NICU, such as the main patients type in NICU, the widely used equipment for brain protection, and technologies for individualized optimal blood supply determination. We aims to bring a new understanding of the clinical technology in NICU.
Xiuyun Liu, is currently a Professor of Biomedical Engineering at Tianjin University. She received her Ph.D. degree in Clinical Neurosciences from University of Cambridge (UK) in 2017, and then joined the Department of Physiological Nursing at University of California, San Francisco, as a postdoctoral researcher for two years. In 2019, she moved to Anesthesiology and Critical Care Medicine Department, Johns Hopkins University to do her second postdoc. She is currently a PI of a national key research and development plan program. Her research mainly focuses on the interaction between critical care medicine and engineering, with the aim of solving the engineering bottleneck problems at bedside and provide optimal treatment or cllinical strategies for front-line doctors. She serves as the main member in several academic societies, and she is the associate editor of Frontiers in Physiology. She has published more than 60 papers, and obtained National Scholarship for Outstanding self-funded international Students, Bill Gates Scholarship. etc.
Talk 3: Soft Wearable Biosensors for Health Monitoring
Speaker: Limei Tian
Wearable sensors provide valuable information related to the health and disease states of individuals. We recently developed biosensors comprised of nanomaterials for the quantification of physical and chemical parameters in situ. One example is a wearable bioimpedance sensor made of conductive nanocomposites to enable cuffless, continuous blood pressure monitoring. The high-performance conductive nanocomposite is soft, moldable and transferrable. The stacked structure of the nanocomposite synergistically integrates the complementary electrical and mechanical properties of the individual components. We patterned the nanocomposite via a simple, low-cost micromolding process and then transferred the patterned large-area electrodes onto various substrates to realize soft, skin-interfaced electrophysiological sensors. Another example is a wearable plasmonic paper-based microfluidic system to continuously and simultaneously quantify sweat loss, sweat rate, and metabolites in sweat. Plasmonic sensors based on surface-enhanced Raman spectroscopy (SERS) are label-free and can identify the analytes of interest via the chemical “fingerprint” information. The well-defined flow kinetics of paper microfluidic devices enable accurate quantification of sweat loss and sweat rate in real time. Reliable quantification can be achieved when the devices are under strain and at high temperatures. These wearable sensors are soft, flexible, and stretchable, providing a robust interface with the skin without inducing chemical or physical irritation.
Limei Tian is an Assistant Professor in the Department of Biomedical Engineering at Texas A&M University. Her research interests include the design, synthesis and fabrication of novel materials and devices that enable advanced health care. She earned her Ph.D. from the Department of Mechanical Engineering and Materials Science at Washington University in St. Louis in 2014. Dr. Tian was a Beckman Institute Postdoctoral Fellow at the University of Illinois at Urbana-Champaign from 2015 to 2018. She is the recipient of Materials Research Society graduate student award, Beckman Institute Postdoctoral Fellowship, and NIH NIBIB Trailblazer Award. She has published more than 60 papers in Nature Biomedical Engineering, Science Advances, Advanced Materials, Advanced Functional Materials, ACS Nano, Nano letters etc.